|Live & Let Live, north-facing side of signboard|
The artist John Crome also produced a version, so the image (or the sentiment it expressed) was clearly popular at the time.
There are some other examples, for example the Load of Mischief, Blewsbury. The Michief, Norwich also once had a version, but recently has gone for something less misogynistic (it's Political Correctness gone mad, I tell you!).
It even travelled across the Pond: in Philadelphia there is (or was) the Man Full of Trouble, dating from 1759.
The original seems to be an engraving in a book (scroll to p. 249) published in 1653 by Dutch poet and humorist, Jacob Cats.
Anyway, where better for such a poor, downtrodden bloke to find refuge from the causes of his burdensome strife than the pub?